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  • 11:36
    Russians hate us?
  • 11:37
    According to street surveys, yes. But there's a catch
  • 11:37
    I'm listening
  • 11:38
    The same street survey then asked 'would you support a nuclear attack on Russia/USA?' And the majority of Americans were like 'fuck yeah, go USA' and all that retarded shit
  • 11:38
    But the Russians turned out to be sensible
  • 11:38
    I highly doubt that
  • 11:38
    And said 'no, no war' Even while believing they are more powerful
  • 11:38
    sounds like bullshit from the russian media
  • 11:38
    Americans are relatively uneducated and ignorant, dude.
  • 11:38
    i agree
  • 11:39
    Just look at how I'm able to criticise my own people and you get all defensive and shit
  • 11:39
    but not supportive of a nuclear attack
  • 11:39
    They were. Hold on
  • 11:39
    Im not getting defensive
  • 11:39
    And it was from an independent channel that also made everyone see Russia's stupidity
  • 11:39
    I agreed most are ignorant and uneducated
  • 11:40
    Not most, don't be so hard on yourself. But the niggers and spics are. Some of them are fine, but..
  • 11:40
    Russia has it's rednecks too. We call'em gopniks
  • 11:40
    I think you're full of shit on the nuclear thing
  • 11:40
    I call BS
  • 11:40
    I can try and find it, but you won't even listen to my 3 second voice recording. So why bother
  • 11:40
    Call BS all you want, you called me damien just an hour ago
  • 11:41
    no find it
  • 11:41
    There goes your credibility, right out the window
  • 11:41
    You won't even fucking watch it
  • 11:41
    guts2 was damien
  • 11:41
    what do I care
  • 11:41
    Should I care?
  • 11:41
    idk who either of those are
  • 11:41
    Because you are also damien
  • 11:41
    Whatever, you autist
  • 11:41
    rofl
  • 11:42
    TRIGGERED
  • 11:42
    I think by now you're also convinced, yet too afraid of admitting that you made a mistake
  • 11:42
    I am triggered. Triggered to the bone
  • 11:42
    lol
  • 11:42
    lol? are you calling me out on league of legends?
  • 11:42
    I will fuck u up mate
  • 11:42
    I will kill u in ur sleep m8 fam
  • 11:42
    alam
  • 11:43
    I will send Jim's arab ass to allahu akhbar you while you're stuffing mexican taco's up your ass
  • 11:43
    I didn't mean that. sorry. I love you, my american friend. Fwiends 4 lief?
  • 11:43
    inb4 mara is lief
  • 11:44
    Russians are weird
  • 11:44
    My rant is over. That felt good
  • 11:44
    I'm basically Belgian (flemish, not fucking wallonian) but yeah. They are weird
  • 11:45
    You should make more of an effort to this civilised debate tho mate, I feel like I'm doing all the work and you're just taking it like a slut
  • 11:45
    Don't be a linguistic slut. be an anal one
  • 11:47
    omg he left
  • 11:47
    why?? WHY???
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Threads /

The (Endo)-cannabinoid system and psycho-biological homeostasis

  • 195 posts

    Both delta 9-THC and cannabidiol may be capable of reducing the neurotoxicity that is mediated in the rat brain by the NMDA-, AMPA-, and kainate receptors. Cannabinoids function as potent antioxidants in cultured neurons"  R Lorenz - Neuro Endocrinol Lett, 2002 -" "Cannabinoids function as neuromodulators and enhance GABA transmission in the GPe [12], possibly by reducing GABA reuptake [13], although the exact mechanism remains unclear" C Zadikoff, PM Wadia, J Miyasaki, R Chen, AE Lang… - Basal Ganglia, 2011 - Elsevier A last example is that cannabinoids function as anxiolytics under certain conditions and doses, a main therapeutic indication of GABA A positive allosteric modulators JA Lile, TH Kelly, LR Hays - Drug and alcohol dependence, 2014 - europepmc.org Dopamine and endogenous cannabinoids function as neurotrans- mitters as well as neuromodulators in the brain, in which they often have opposing effects on nerve function S Fan, S Yazulla - Visual neuroscience, 2005 - Cambridge Univ Press  Some studies describing the effects of cannabinoids on the system...  now endocannanbinoids  https://arxiv.org/abs/cond-mat/0208590 Dreams, endocannabinoids and itinerant dynamics in neural networks: re elaborating Crick-Mitchison unlearning hypothesis  Dreams, endocannabinoids and itinerant dynamics in neural networks: re elaborating Crick-Mitchison unlearning hypothesis [cond-mat/0208590] Dreams, endocannabinoids and itinerant dynamics in neural networks: re elaborating Crick-Mitchison unlearning hypothesis In this work we reevaluate and elaborate Crick-Mitchison's proposal that REM-sleep corresponds to a self-organized process for unlearning attractors in neural networks. This reformulation is made at the face of recent findings concerning the intense activation of the amygdalar complex during REM-sleep, the role of endocannabinoids in synaptic weakening and neural network models with itinerant associative dynamics. We distinguish between a neurological REM-sleep function and a related evolutionary/behavioral dreaming function. At the neurological level, we propose that REM-sleep regulates excessive plasticity and weakens over stable brain activation patterns, specially in the amygdala, hippocampus and motor systems. At the behavioral level, we propose that dream narrative evolved as exploratory behavior made in a virtual environment promoting "emotional (un)learning", that is, habituation of emotional responses, anxiety and fear. We make several experimental predictions at variance with those of Memory Consolidation Hipothesis. We also predict that the "replay" of cells ensembles is done at an increasing faster pace along REM-sleep.

     

  • 1,515 posts

    luv me sum ah-7921

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